Introduction: Coronary Artery Disease involves atherosclerotic plaque formation in lumen causing impairment of blood flow to myocardium and is a major cause of death having incidence of 7%–13% urban and 2–7% rural. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels, triggering coronary artery disease (CAD) and release of pro-inflammatory mediators and cytokines into the circulation stimulate the production and release of acute-phase proteins and inflammatory cells, resulting in a state of low-grade systemic inflammation and this has an impact on blood vessels, encouraging the instability and rupture of atherosclerotic plaque and precipitating sudden cardiac and cerebral events. There is even significant influence of anti-asthmatic medications on CAD development. Materials and Methods: An open labelled, single-arm, prospective observational case study. A 74-year-old male complained of hrudshoola, arohana ayasa, padashotha, parshvashoola and kasa since 3 years with a history of adulthood asthma and hypertension (15 years) and was on medication for the same. He was diagnosed with CAD – triple vessel disease s/p CABG, mild LV systolic dysfunction and grade I diastolic dysfunction. He visited Kayachikitsa OPD TGAMC, Ballari. On the same day, spirometry showed severe bronchial obstruction with normal chest X-ray. He was treated with Tulasi churna 1 tsf OD with ushna jala before food for 7 days. After attaining nirama avastha, sadyovirechana with Nimbamrutadi castor oil 50 ml with 100 ml milk was given and number of vegas were 8. Next day, sthanika abhyanga over urah pradesha with salavana murchita tila taila followed by nadisweda was done for 7 days. Then shamanaushadhi like Hinguvachadi churna 1 tsf TID with ushna jala before food, Punarnavasava 60 ml TID with 60 ml ushna jala after food and Prabhakara vati 2 BD with ushna jala after food as hrudrasayana was given for 69 days. Observations and Results: Subjective improvement was seen in shotha, ayasa and hrudshoola, and objective improvement was seen in spirometry with changes from severe obstruction to moderate obstruction, with improvement in FEV1/FVC from 56% to 72%. Discussion and Conclusion: Alkaloids and glycosides present in Tulasi churna act as cardiostimulants. It is a proven bronchodilator and immunomodulator. Tulasi, due to its teekshna and ushna guna, acts as vata-kapha hara and shwasa hara, and due to tikta guna acts as hridya. Salavana taila sthanika abhyanga and nadi sweda cause kaphavilayana and their swedana effect causes vasodilation, thereby improving blood flow and correcting oxygen mismatch. Hinguvachadi churna acts as vaatanulomana, shothahara, hridshoolahara and does srotovishodhana, thus correcting vimarga gamana of udana and vyana vata. Punarnavasava is anti-inflammatory, shothahara, acts on high cholesterol and is kasahara. Prabhakara vati is a hrudrogahara rasayana, does hrudbalya and due to its yogavahi property acts on high cholesterol, asthma and inflammation.
CAD, Asthma, Tulasi churna, Salavana taila, Nadisweda, Nimbamrutadi castor oil, Hinguvachadi churna, Punarnavasava, Prabhakara vati.
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